[Acute disseminated encephalomyelitis (ADEM) associated with cytomegalovirus infection--a case report].
نویسندگان
چکیده
A 60-year-old woman was admitted to our hospital because of developing fever, visual loss, weakness in right upper limb, walking difficulty and difficulties of urination and defecation. There were memory disturbance, optic neuritis, ataxia and myelopathy. CSF cells and protein were increased. Cytomegalovirus (CMV) antibodies in the CSF were increased. T2-weighted images of brain MRI showed diffuse high signal intensity lesions in white matter. Gadolinium-enhanced MRI of cervical spinal cord showed diffuse spotty enhanced lesions. Corticosteroid treatment improved clinical symptoms and anti-CMV antibodies in the CSF. This is the first case report of ADEM associated with CMV infection.
منابع مشابه
Acute Disseminated Encephalomyelitis; A Rare Iranian Case Report
Acute disseminated encephalomyelitis (ADEM) is a monophasic clinical syndrome, characterized by immune-mediated demyelination of central nervous system neurons, which yield extensive damage in the brain and spinal cord.It usually affects children and young adults following infections or immunization. Here we describe a 9- year-old Fars female presented with acute onset of psychotic disorder, o...
متن کاملPediatric B Cell Acute Lymphoblastic Leukemia presenting with Paraneoplastic Acute Disseminated Encephalomyelitis
Acute Disseminated Encephalomyelitis (ADEM) is a monophasic demyelinating disease most often triggered by infection or immunization, though associations with malignancy and stem cell transplant have been described. We described the case of a four-year-old boy with new-onset neurological symptoms associated with ADEM, acute leukemia, and equivocal evidence of Mycoplasma pneumoniae infection. He ...
متن کاملCytomegalovirus-associated encephalomyelitis in an immunocompetent adult: a two-stage attack of direct viral and delayed immune-mediated invasions. case report
BACKGROUND It is clinically rare to find cytomegalovirus (CMV)-associated encephalomyelitis in immunocompetent adults. Here, we present the case of an adult patient who developed acute transverse myelitis that was followed by immune-mediated disseminated encephalomyelitis. CASE PRESENTATION A 38-year-old man developed acute paraplegia with paresthesia below the level of the T7-8 dermatome. Bo...
متن کاملAn infant with steroid-refractory cytomegalovirus-associated ADEM who responded to immunoglobulin therapy.
Acute disseminated encephalomyelitis (ADEM) develops via an immunological mechanism. We encountered a 10-month-old infant with a rare pathogenesis of cytomegalovirus (CMV)-related ADEM. The patients complaints were; protracted fever; consciousness disorder; and affected cervical stability. Cerebral magnetic resonance imaging (MRI) 9 days after onset, revealed a disseminated lesion, suggesting A...
متن کاملEnlarging the Spectrum of Inflammatory/Post-Infectious Acute Disseminated Encephalomyelitis: A Further Case Associated with Neurotoxocariasis
Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder with an acute or subacute onset, typically of a monophasic nature, which affects multifocal areas of the central nervous system. ADEM is commonly associated with an antecedent or concomitant infection that is usually viral. However, in the last few years, several published reports have indicated an association...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Rinsho shinkeigaku = Clinical neurology
دوره 34 5 شماره
صفحات -
تاریخ انتشار 1994